Axial: https://linktr.ee/axialxyz
Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company . We are excited to be in business with you - email us at info@axialvc.com
GreenLight Biosciences uses cell-free RNA manufacturing for human health and agriculture. Founded and led by Andrey Zarur @andreyzarur, GreenLight got started in 2008 to build a cell-free platform for RNA, now bringing their manufacturing scale from dsRNA to mRNA.
The technology is actually based on work from James Swartz’ (Sutro Co-Founder) group at Stanford. From yeast, cellular RNA is produced & depolymerized with a nuclease. The RNA building blocks are then put together into a longer RNA based on a DNA template.
GreenLight uses this platform for agriculture with their lead pesticide for Colorado potato beetle near commercialization. IVT for RNA production doesn’t scale for agriculture. GreenLight’s cell-free tech has brought down the cost of dsRNA to <$1/gram at 2K liters a batch.
RNA has a wide-range of applications given its transient expression & fast development. With manufacturing (and IP) as key problems, GreenLight is bringing their scale from dsRNA to mRNA for vaccines & gene therapies. Learn more about GreenLight here: https://www.greenlightbiosciences.com/